Papel del coactivador PGC-1α en el balance energético. Importancia en la producción de bovinos de engorda.

  • Patricia García-Rojas Montiel Universidad Nacional Autónoma de México (UNAM)
  • Anaid Antaramian Unidad de Proteogenómica, Instituto de Neurobiología, UNAM, Querétaro
  • Armando Shimada Miyasaka UNAM
  • Francesc Villarroya Gombau Universitat de Barcelona
  • María Ofelia Mora Izaguirre UNAM

Abstract

The importance of dietary fat in the expression of multiple genes is clear, in the case of beef cattle, fat in the form of fatty acids (saturated or unsaturated), vitamin A (mainly retinoic acid), or carotenoids (β-carotene, lutein, licopen and their metabolites), is obtained constantly from the dietary feed or from pasture. This review tries to summarize the advances in the study of some of the transcription factors and their co-regulators, specifically coactivator PGC-1, which has been observed to affect the transcription of genes involved in energy homeostasis. The capacity of dietary lipids or their metabolic products, to influence on PGC-1α, due in part to the presence of an element of answer to PPAR in its genic promoter, which appears to be conserved in different species of mammals including bovines. It might be important to find nutrients or other types of compounds, that could act as ligands of the factors of transcription of specific genes, that control metabolic processes such as gluconeogenesis and lipolysis in rumiants so in a near future they would contribute to improve the production in the specie.

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Author Biographies

Patricia García-Rojas Montiel, Universidad Nacional Autónoma de México (UNAM)
Programa de Posgrado en Ciencias de la Producción y de la Salud Animal
Armando Shimada Miyasaka, UNAM
Laboratorio de Rumiología y Metabolismo Nutricional (RuMeN). Secretarías de Investigación y de Posgrado. Facultad de Estudios Superiores-Cuautitlán, UNAM. Blvd. B. Quintana 514-D, Arboledas. Querétaro, Qro. 76140, México.
Francesc Villarroya Gombau, Universitat de Barcelona
Departamento de Bioquímica y Biología Molecular e Instituto de Biomedicina (IBUB), Universitat de Barcelona y CIBER Fisiopatología de la Obesidad y Nutrición. Av. Diagonal 645, Barcelona. 08028, España.
María Ofelia Mora Izaguirre, UNAM

Profesor Titular B. Tiempo Completo. Definitivo. Laboratorio de Rumiología y Metabolismo Nutricional. Facultad de Estudios Superiores-Cuautitlán UNAM

Published
2010-03-18
How to Cite
García-Rojas Montiel, Patricia, Anaid Antaramian, Armando Shimada Miyasaka, Francesc Villarroya Gombau, and María Ofelia Mora Izaguirre. 2010. “Papel Del Coactivador PGC-1α En El Balance energético. Importancia En La producción De Bovinos De Engorda.”. Archivos Latinoamericanos De Producción Animal 16 (2). https://ojs.alpa.uy/index.php/ojs_files/article/view/612.
Section
Original paper